I would say the game experience is very different from one player to the next but this is what is similar:
Since the game is in 'real time', in every game we are all playing the same day of the year, in the same town. Thus, in everyone's town right now (assuming you set it right) it is Jan 3rd, Winter. Everyone had New Year's in their town on the 31st, for example. Also, because it's winter everywhere, we all get to build snowmen. That's just a function of it being winter.
The towns are also very similar in that they will always have a beach, a town hall, a store, trees, etc. But the terrain is randomly generated, like Sim City.
What is different:
Every player is different, either male or female and with slightly different features based on how they answered some questions. The location of their house is different, but we all start with the same size house and the same mortgage.
In the town: ALL the NPC's will differ from town to town, and they all have different personalities. The NPC's are really the crux of your gameplay experience. For example, in my town, I have three squirrels, a cat, a duck, a bunny, a penguin and a rhino. (thank god one of the squirrels moved out, ugh.) You'll never get the same answer from anyone, and the animals are always moving out and in.
The items that you get in the store are mostly random everyday in every town (except for utility things like axe, shovel, plants etc.), and you get different items randomly from different NPC's.
Therefore, it is a very different game for everyone: Everyone will interact with the different people in the town differently and will get different items. There are THOUSANDS of 'for house' items. Everyone will choose different items and clothes for themselves based on their personality! But the *game* is played the same in every town.
THE END OMG.
Added after 9 minutes:
Hey guys, you were right about the clock on the phone... that's weird though, you can't get to that option once you 'wake up'!
Dave: I'm rageing lesbian trapped in a man's body.
Sucros: You can't learn to cook without learning a little french, you can't discuss softcore gay porn without learning a little japanese.